Orthotopic CDX Models

Orthotopic mouse models play a pivotal role in cancer research and drug development. These models entail the implantation of tumor cells into a mouse's organ of origin, closely mirroring the natural tumor environment, thus providing better clinical predictivity than subcutaneous approaches. Orthotopic models faithfully replicate the primary tumor site, enabling more precise examination of tumor growth, interactions with stromal cells and immune elements, and disease progression, including metastasis.

LIDE has established over several luciferace-labeled models for use in your preclinical studies. We could also establish new orthotopic models complimentary if you can't find them elsewhere.